The Buffalo Bills are set to host the New England Patriots in Week 16. Following a dominant victory over the Detroit Lions last week, the Bills are in excellent shape as the playoffs draw near. They remain in contention for the AFC’s top seed and a first-round bye, making every game crucial. Meanwhile, the Patriots are seeing promising development from rookie quarterback Drake Maye but continue to struggle in other areas. As the divisional matchup approaches, here are some bold predictions for the Bills in Week 16.
Injury Update and Availability
The Bills enter the week with minimal injury concerns. Left tackle Dion Dawkins missed Thursday’s practice due to an unusual incident—a plane crashed in his backyard, preventing him from making it to the facility. However, he is expected to play on Sunday. Tight end Dalton Kincaid and wide receiver Keon Coleman, who returned last week, are ready to go. Additionally, Rasul Douglas, Damar Hamlin, and Matt Milano were limited in practice but remain in contention to play.
This game marks the first of two matchups between Buffalo and New England in the season’s final two weeks. How will this one unfold? Here are the bold predictions for the Bills in Week 16:
Josh Allen Shines with Four Touchdowns, No Interceptions
Josh Allen is the current favorite to win his first MVP award. Despite a stellar career, the MVP trophy has eluded him, and he has an opportunity to solidify his case against a struggling Patriots defense. With Christian Barmore out and Allen avoiding matchups with Christian Gonzalez, he is poised to deliver four touchdowns without a single interception.
Allen has been outstanding over the past two weeks, even though the Bills dropped one of those games. With Lamar Jackson still in the MVP race, Allen needs to maintain his high level of play, especially against weaker opponents like the Patriots and Jets. His performance will delight fantasy football managers and Bills fans alike.
James Cook and Amari Cooper Find the End Zone
While Allen racks up touchdowns, he’ll also distribute the ball effectively in what is expected to be a lopsided victory. Running back James Cook has emerged as a key offensive piece, capable of breaking big runs and drawing defensive attention away from Allen. Meanwhile, wide receiver Amari Cooper, acquired at the trade deadline, is due for a breakout performance after a relatively quiet stretch. Both are predicted to score touchdowns in this game.
The Bills’ offensive depth is impressive, even after trading Stefon Diggs. With Cooper joining a group that includes Dalton Kincaid, Dawson Knox, and Cook, the team has multiple red-zone threats, making their attack nearly impossible to contain.
Bills Defense Holds the Patriots Under 20 Points
The Bills defense, criticized for its late-game performance against Jared Goff and the Lions, needs a strong rebound. Facing an inconsistent Patriots offense led by rookie Drake Maye provides the perfect opportunity. Buffalo is expected to limit New England to fewer than 20 points, contributing to a decisive victory.
The Bills are heavy favorites, with FanDuel listing them as 14.5-point favorites and a money line of -1200. The game’s over/under is set at 46.5, suggesting confidence in Buffalo’s ability to dominate both offensively and defensively.
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